69 Results for "

Azadirachta indica A. Juss.

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "Azadirachta indica A. Juss." in MCE Product Catalog:

8
Schaftoside
Schaftoside
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8 Publications Verification
Cat. No.: HY-N0703
CAS No.: 51938-32-0
Category:  

Flavonoids Eleusine indica (Linn.) Gaertn. Leguminosae Flavones Gramineae Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Toll-like Receptor (TLR) MyD88 Dynamin Mitochondrial Metabolism Autophagy

Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission .
5
Garcinol
Garcinol
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5 Cited Publications
Cat. No.: HY-107569
CAS No.: 78824-30-3
Purity:  ≥99.0%
Category:  

Guttiferae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Garcinia indica

Target:  

Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite

Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
2
Nimbolide
Nimbolide
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2 Cited Publications
Cat. No.: HY-116035
CAS No.: 25990-37-8
Purity:  99.79%
Category:  

Triterpenes Terpenoids Plants Azadirachta indica A. Juss. Disease Research Fields Meliaceae Cancer

Target:  

Wnt NF-κB CDK Apoptosis

Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .
Salannin
Salannin
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Cat. No.: HY-123026
CAS No.: 992-20-1
Purity:  99.30%
Category:  

Infection Triterpenes other families Terpenoids Plants Disease Research Fields

Target:  

Bacterial

Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria .
1-Eicosanol
1-Eicosanol
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Cat. No.: HY-W004263
CAS No.: 629-96-9
Synonyms: Arachidyl alcohol
Category:  

Natural Products other families Plants Disease Research Fields Inflammation/Immunology Hypericum carinatum

Target:  

Environmental Pollutants Fungal

1-Eicosanol (Arachidyl alcohol) is a long-chain fatty alcohol and volatile organic compound that can be isolated from the leaves of Leea indica and produced by Bacillus velezensis ZJ1. 1-Eicosanol inhibits mycelial growth of Alternaria solani and Botrytis cinerea. 1-Eicosanol is applicable to research related to tomato early blight and tomato gray mold .
Quisqualic acid
Quisqualic acid
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Cat. No.: HY-12597
CAS No.: 52809-07-1
Purity:  ≥98.0%
Synonyms: L-Quisqualic acid
Category:  

Combretaceae Ketones, Aldehydes, Acids Plants Quisqualis indica Linn.

Target:  

iGluR mGluR

Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica .
Mauritianin
Mauritianin
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Cat. No.: HY-N5038
CAS No.: 109008-28-8
Category:  

Flavonols Erythrina stricta Roxb. Plants Compositae Acalypha indica Linn. Flavonoids Phenols Polyphenols Euphorbiaceae Disease Research Fields Cancer

Target:  

Topoisomerase

Mauritianin is an orally active kaempferol glycoside. Mauritianin can be isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Mauritianin has hepatoprotective, neuroprotective, and renoprotective activities. Mauritianin increases vascular tone when used in combination with Alcesefoliside (HY-N5049) .
Azadirachtin B
Azadirachtin B
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Cat. No.: HY-133108
CAS No.: 106500-25-8
Purity:  99.17%
Category:  

Triterpenes Metabolic Disease Plants Biological Pesticide Research Agricultural Research Infection other families Terpenoids Disease Research Fields Inflammation/Immunology

Target:  

EBV Parasite Phosphatase Influenza Virus

Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .
Aristolochic acid D
Aristolochic acid D
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Cat. No.: HY-N1465
CAS No.: 17413-38-6
Synonyms: Aristolochic acid-IVa
Category:  

other families Monophenols Ketones, Aldehydes, Acids Phenols Plants Disease Research Fields Cancer

Target:  

Phosphodiesterase (PDE) CDK Interleukin Related

Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC50: 4.673 μM) and CDK2 (IC50: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .
Ovatodiolide
Ovatodiolide
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Cat. No.: HY-118921
CAS No.: 3484-37-5
Category:  

Labiatae Terpenoids Diterpenoids Plants Artemisia persica Boiss.

Target:  

Apoptosis

Ovatodiolide is a compound that can be isolated from Anisomeles indica. Ovatodiolide has anti-bacterial and anti-inflammatory properties. Ovatodiolide also has anti-cancer activity that induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways .
Cucurbitacin F
Cucurbitacin F
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Cat. No.: HY-N12461
CAS No.: 5939-57-1
Category:  

Triterpenes Hemsleya gigantha W. J. Chang Terpenoids Cucurbitaceae Plants

Target:  

Bacterial Caspase Apoptosis

Cucurbitacin F is a tetracyclic protostane-type triterpenoid with low toxicity, antibacterial and anti-inflammatory activities, and is also a related compound of Cucurbitacin B (HY-N0416). Cucurbitacin F widely exists in plants such as Cucurbitaceae plants, Quisqualis indica and Sorbaria sorbifolia. Cucurbitacin F acts as an actin aggregator and reduces cell viability in a dose-dependent manner. Cucurbitacin F induces apoptosis by triggering G2/M phase cell cycle arrest and activating the caspase-3-dependent apoptosis .
Nimbin
Nimbin
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Cat. No.: HY-N3187
CAS No.: 5945-86-8
Category:  

Infection Other Terpenoids other families Neurological Disease Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Flavivirus Dengue Virus Fungal Bacterial Histamine Receptor

Nimbin is an orally active intermediate limonoid found in Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin is promising for research of neurodegenerative diseases and viral infections .
Norwogonin-8-O-glucuronide
Norwogonin-8-O-glucuronide
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Cat. No.: HY-N12394
CAS No.: 118525-47-6
Category:  

Flavonoids Flavones Labiatae Amberboa moschata (L.) DC. Plants

Target:  

Reactive Oxygen Species (ROS) NO Synthase

Norwogonin-8-O-glucuronide is a glucuronide that can be isolated from Scutellaria indica. Norwogonin-8-O-glucuronide has anti-inflammatory activity. Norwogonin-8-O-glucuronide is a flavone glycoside. Norwogonin-8-O-glucuronide inhibits NO production in macrophage RAW264.7 cells with an IC50 above 30 μM .
28-Deoxonimbolide
28-Deoxonimbolide
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Cat. No.: HY-N1710
CAS No.: 126005-94-5
Category:  

Triterpenes Terpenoids Plants Azadirachta indica A. Juss. Meliaceae

Target:  

Apoptosis Caspase

28-Deoxonimbolide is a Nimbin (HY-N3187) type limonoid, that can be isolated from Azadirachta indica seed extracts. 28-Deoxonimbolide shows anticancer activity. 28-Deoxonimbolide induces apoptotic cell death in HL60 cells via both the mitochondrial- and the death receptor-mediated pathways .
Methyl citrate
Methyl citrate
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Cat. No.: HY-N9540
CAS No.: 26163-61-1
Category:  

Cactaceae Ketones, Aldehydes, Acids Opuntia ficus-indica (L.) Mill. Plants

Target:  

Monoamine Oxidase

Methyl citrate is a Monoamine oxidase B (MAO-B) inhibitor (IC50=0.23 mM). Methyl citrate is isolated from the fruits of Opuntia ficus-indica var. saboten Makino .
Pyraclonil
Pyraclonil
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Cat. No.: HY-17531
CAS No.: 158353-15-2
Target:  

Environmental Pollutants Herbicide

Research Areas:  

Others

Pyraclonil is a proporphyrinogen oxidase (PPO) inhibitor. Pyraclonil is a herbicide agent and is highly effective in controlling the susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations . Pyraclonil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Azadirachtin H
Azadirachtin H
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Cat. No.: HY-N16474
CAS No.: 134788-15-1
Category:  

Tetracyclic Triterpenoids Terpenoids Plants Azadirachta indica A. Juss. Meliaceae

Target:  

Drug Derivative

Azadirachtin H is a triterpenoid found in Azadirachta indica. Azadirachta indica shows anti-infection, anti-inflammatory and anticancer activities. Azadirachtin H can be used for the researches of cancer, infection and inflammation .
Epoxyazadiradione
Epoxyazadiradione
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Cat. No.: HY-N10096
CAS No.: 18385-59-6
Category:  

Infection Triterpenes other families Terpenoids Plants Disease Research Fields Biological Pesticide Research Agricultural Research

Target:  

Parasite

Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (Ki, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human .
Azadiradione
Azadiradione
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Cat. No.: HY-N9615
CAS No.: 26241-51-0
Category:  

Triterpenes other families Neurological Disease Terpenoids Plants Disease Research Fields Inflammation/Immunology Biological Pesticide Research Agricultural Research

Target:  

HSP

Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities .
Acalyphin
Acalyphin
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Cat. No.: HY-122764
CAS No.: 81861-72-5
Category:  

Gramineae Plants Oryza sativa subsp. indica Kato Saccharides

Target:  

Others

Acalyphin, a cyanogenic glucoside, is nature product that could be isolated from the aerial parts of Acalypha indica .
Assay Types